Polyglycolic Acid PGA

Unlike PLA (absorbed slowly), PGA is absorbed within a few months postimplantation due to greater hydrolytic susceptibility. In vitro experiments have shown an effect on degradation by enzymes, buffer, pH, annealing treatments, and gamma irradiation.
Since PGA is susceptibility to degradation from moisture and gamma rays, use low humidity ethylene oxide gas sterilization procedures and moisture-proof packaging. Acceleration of in vivo degradation due to gamma irradiation has been exploited to create devices where early fragmentation is desired.